There?s a long list of celebrities who?ve been diagnosed with breast cancer ? including Kylie Minogue (36), Robin Roberts (49) and author Judy Blume (74). And thousands more find out they have the condition every year.
But what does this have to do with your preteen daughter? Research shows that girls with excess weight and insulin resistance have a greater chance of developing breast cancer. Unfortunately, more than 30 percent of kids are overweight, and that?s a trigger for type 2 diabetes, heart disease and, yes, breast cancer. We know you want to help your daughter stay healthy. Here?s how:
? Eliminate the five food felons. That?s drinks and foods with added sugars or syrups, all grains but 100 percent whole grains, trans fats and most saturated fat.
? Serve up three meals and two snacks a day. Kids with a steady supply of healthy food have fewer binges on fast food and stay trimmer. Make sure she gets plenty of omega-3s (in avocados, walnuts and canola oil) and omega-9s (in olive oil).
? Get her up and moving. Kids 6 to 17 need at least 60 minutes a day of mostly aerobics (walking, playing outdoor games), plus bone-strengthening (jumping rope or running) and muscle-building (gymnastics for kids under 14; light weightlifting for older kids).
When you fuel her with good stuff and teach her how to make smart lifestyle choices, she?ll thank you for decades.
The You Docs ? Mehmet Oz, host of ?The Dr. Oz Show? and Mike Roizen of Cleveland Clinic ? are authors of ?YOU: Losing Weight.? To submit questions, go to www.RealAge.com. A King Features syndicate.
NEW YORK (AP) ? How cool is this: Johnny Depp is going to help run a publishing imprint.
Already on the list of books is one by Bob Dylan, "The Unraveled Tales of Bob Dylan," which aims to set the record straight on the songwriter's enigmatic life and career and will be based in part on interviews with Dylan by best-selling historian Douglas Brinkley.
Depp's imprint will share its name with his production company, Infinitum Nihil, meaning "Nothing is forever." The imprint will be part of HarperCollins Publishers, which announced Monday that Depp will seek "authentic, outspoken and visionary ideas and voices."
"I pledge, on behalf of Infinitum Nihil, that we will do our best to deliver publications worthy of peoples' time, of peoples' concern, publications that might ordinarily never have breached the parapet," Depp said in a statement released by HarperCollins. "For this dream realized, we would like to salute HarperCollins for their faith in us and look forward to a long and fruitful relationship together."
Brinkley, who recently wrote a cover story on Dylan for Rolling Stone, said he and Depp thought the Dylan book was "the ideal way" to inaugurate the Infinitum Nihil series.
"Bob has been very warm and forthcoming with us," Brinkley said in a statement. "His music has inspired us both deeply since we were teenagers."
The Dylan book is scheduled for 2015. Dylan and Brinkley also will collaborate on the editing and publication of a previously announced novel by one of Dylan's heroes, folk musician Woody Guthrie, who died in 1967. The novel, "House of Earth," was completed by Guthrie in 1947 but was only recently discovered. It's scheduled for January.
Depp, whose movies include "Edward Scissorhands" and the "Pirates of the Caribbean" series, already has ties to the book world. He was a close friend of Hunter Thompson and starred in film adaptations of Thompson's "Rum Diary" and "Fear and Loathing in Las Vegas." He also narrated parts of the audio edition of Keith Richards' memoir "Life."
Other celebrities with their own imprints include Chelsea Handler and Rachael Ray.
Rapamycin, a drug used to prevent rejection in transplants, could delay the onset of neurodegenerative diseases such as Alzheimer's and Parkinson's. This is the main conclusion of a study published in the Nature in which has collaborated the researcher Isidro Ferrer, head of the group of Neuropathology at the Bellvitge Biomedical Research Institute (IDIBELL) and the Bellvitge University Hospital and Full Professor of Pathological Anatomy at the University of Barcelona. The research was led by researchers from the International School for Advanced Studies (SISSA) in Trieste (Italy).
The collaboration of the research group led by Dr. Ferrer with SISSA researchers began five years ago when they observed that Parkinson's patients showed a deficit in UCHL1 protein. At that time, researchers didn't know what mechanism produced this deficit. To discover it a European project was launched. It was coordinated by the Italian researchers and participated by other European research groups, including the group led by Dr. Ferrer. The project, called Dopaminet, focused on how dopaminergic neurons (brain cells whose neurotransmitter is dopamine) are involved in Parkinson's disease.
Contrary to most common hypothesis that a DNA fragment encodes a protein through a messenger RNA molecule, the researchers found that it also works in reverse. They found a balance between the protein and its mirror protein, which is configured in reverse, and they are mutually controlled. If the protein mirror is located in the nucleus of the cell, it does not interact with the protein, while if it is in the cytoplasm, then both of them interact.
In the case of Parkinson's disease the protein UCHL1 appears reduced and also its mirror protein is localized in the nucleus, and in the cytoplasm. Thus, the researchers sought a method to extract the mirror protein from the nucleus and made it interact with the original UCHL1 protein. The authors found that rapamycin was able to extract them from the nucleus. The drug allows the two proteins, the UCHL1 and its mirror, hold together in the cytoplasm, which would correct the mistakes that occur in Parkinson's disease.
This in vitro research has allowed describing a new unknown mechanism. It is necessary that the UCHL1 mirror protein should accumulate in the nucleus and escape from the cytoplasm and join the UCLH1 protein. The combination of both makes the system work.
"The rapamycin can not cure Parkinson's disease, but it may delay the onset of neurodegenerative diseases such as Alzheimer's and Parkinson's itself. Rapamycin can protect and delay the beginning of these diseases. It can complete the treatment, but it should be combined with other existing treatments", explains Isidro Ferrer.
Anyway, it is still far its application in patients. The next step is to validate these results in animal models and study the effects of rapamycin in combination with other drugs.
###
Claudia Carrieri, Laura Cimatti, Marta Biagioli, Anne Beugnet, Silvia Zucchelli, Stefania Fedele, Elisa Pesce,Isidre Ferrer, Licio Collavin, Claudio Santoro, Alistair R. R. Forrest, Piero Carninci, Stefano Biffo, Elia Stupka & Stefano Gustincich. Long non-coding antisense RNA controls Uchl1 translation through an embedded SINEB2 repeat. Nature. DOI: 10.1038/nature11508
IDIBELL-Bellvitge Biomedical Research Institute: http://www.idibell.cat
Thanks to IDIBELL-Bellvitge Biomedical Research Institute for this article.
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On his show, Comedian Rodney Perry covers arts and entertainment, everything from comedy and politics to music and acting, with his signature comedic slant.
MashUp Radio is a 30-minute podcast that discusses the fusion of technology, life, culture and science. Host Peter Biddle, engineer and executive for Intel?s Atom Software, dishes up a thought-provoking discussion.
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Listeners get an earful on The Halli Casser-Jayne Show, Talk Radio for Fine Minds. Whether it?s the current political cocktail or the latest must-read award-winning book, Halli tackles all topics and likes to stir ? and sometimes shakes ? things up.
Host John Martin interviews the nation's leading entrepreneurs and small biz experts to educate small business owners on how to be successful. Past guests have included Emeril Lagasse and Guy Kawasaki.
The Movie Geeks share their passion for the art through interviews with the stars of and creative minds behind your favorite flicks and pay tribute to big-screen legends. From James Cameron and Francis Ford Coppola to Ellen Burstyn and Robert Duvall, The Geeks have got'em all.
Sylvia Global presents global conversations pertaining to women, wealth, business, faith and philanthropy. Sylvia has interviewed an eclectic mix from CEOs and musicians to fashion designers and philanthropists including Randolph Duke and Ne-Yo.
Seasoned entertainment reporter Robin Milling gets up close and personal with the world's most compelling celebs. From Michael Douglas to Katie Holmes to Kevin Kline to Ashley Judd to America Ferrera, she sits down in person each week with each and every A-lister.
Mr. Media host Bob Andelman goes one-on-one with the hottest, most influential minds from the worlds of film, TV, music, comedy, journalism and literature. That means A-listers like Kirk Douglas, Christian Slater, Kathy Ireland, Rick Fox, Chris Hansen and Jackie Collins.
Paula Begoun, best-selling author of Don't Go to the Cosmetics Counter Without Me, separates fact from fiction on achieving a radiant, youthful complexion at any age. She?s regularly joined by health and beauty experts who offer the latest on keeping your skin in tip-top shape.
NEW YORK -- Former "Bachelorette" Ashley Hebert (AY'-behr) will have quite a wedding video.
Hebert and fiance J.P. Rosenbaum have signed a deal with ABC to film their marriage ceremony.
"The Bachelorette: Ashley and J.P.'s Wedding" will air in December. It will include everything from Hebert's dress fitting and wedding planning to the bachelor and bachelorette parties.
Hebert competed for Brad Womack's affections on the 15th season of "The Bachelor." She was then chosen to be the next "Bachelorette." The dating reality show aired last year.
Hebert, 28, is a dentist in Philadelphia. Rosenbaum, 35, works in construction in New York.
Filming is under way for the next season of "The Bachelor," with 24 women competing for the affection of Dallas businessman Sean Lowe. The new season will premiere in January.
Tap into the essentials of the week ahead and re-live the highlights of the past week with Corona Slice, as we serve up an executive summary of what every fan should know, along with a look at the best in social media.
LOOKING AHEAD
Who?s Playing This Week? There are three ATP World Tour 250 events in Stockholm, Vienna and Moscow.
If Stockholm Open: Top 10 stars Jo-Wilfried Tsonga (No. 1 seed) and Tomas Berdych (No. 2 seed) headline the field in Stockholm. Berdych and Tsonga are currently in line to qualify for the season-ending Barclays ATP World Tour Finals, sitting in the sixth and eighth positions in the South African Airways ATP Rankings Race To London. Third seed Nicolas Almagro is 10th in the Race To London and makes his debut, while 2010 finalist Florian Mayer is seeded fourth. Facebook | Twitter |?Website
Erste Bank Open: Top seed Juan Martin del Potro is back in action for the first time since representing Argentina in the Davis Cup semi-finals. Del Potro is ranked seventh in the Race To London and is joined by contender Janko Tipsarevic. The second seed is on the outside looking in, ranked ninth. Two former champions, third seed Tommy Haas (2001) and fourth seed Jurgen Melzer (2009-2010) also feature in the draw. Facebook |?Website
Kremlin Cup: World No. 20 Alexandr Dolgopolov is the top seed, looking to improve on a quarter-final showing in 2010. Andreas Seppi is seeded second and Viktor Troicki, who lifted his first ATP World Tour trophy at the event in 2010, is the No. 3 seed. Sixth-seeded home favourite Nikolay Davydenko (pictured above)?returns in his quest to capture a fourth trophy at the event, triumphing in 2004, 2006 and 2007. Facebook | Twitter | Website
Potential Milestones (Career match wins as of 15 October 2012) Stockholm ? Singles Mikhail Youzhny ? 395 wins Feliciano Lopez ? 295 wins Kevin Anderson ? 95 wins Sergiy Stakhovsky ? 95 wins ? Stockholm ? Doubles Robert Lindstedt ? 247 wins Marcelo Melo ? 197 wins Aisam-Ul-Haq Qureshi ? 148 wins ? Vienna ? Singles Tommy Haas ? 499 wins ? Vienna ? Doubles Andre Sa ? 199 wins ? Moscow ? Singles Benjamin Becker ? 97 wins ? Moscow ? Doubles Rajeev Ram ? 97 wins ? Rankings Movers Tomas Berdych 6 (+1 spot) Jo-Wilfried Tsonga 7 (-1 spot) Radek Stepanek 35 (+6 spots) Benoit Paire 46 (+6 spots) ? Career High Lukas Lacko 51 (+8 spots) ? Career High Matthew Ebden 123 (-53 spots) Jack Sock 165 (+55 spots) ? Career High
Tidbits ??Roger Federer celebrates his 300th week atop the South African Airways ATP Rankings. Read our tribute...
Birthdays 15 October ? Jesse Levine (25) 16 October ? Philipp Kohlschreiber (29) 20 October ? Flavio Cipolla (29) 21 October ? Bernard Tomic (20)
Player To Watch: Janko Tipsarevic The World No. 9 looks to add valuable points at the Erste Bank Open in his bid to qualify for the Barclays ATP World Tour Finals. Tipsarevic is just outside the qualification cutline in ninth place, the position he finished in last year before competing as an alternate. He has a 53-22 season record, highlighted by his first clay-court title in Stuttgart (d. Monaco) and semi-final showings at the ATP World Tour Masters 1000 events in Madrid (l. to Federer) and Toronto (l. to Djokovic). The Serb also equalled his best major performance by reaching the US Open quarter-finals for a second straight year (l. to Ferrer).
How To Watch Follow all of the action from Stockholm (Not available in Sweden, USA and Russia) and Vienna (Not available in Austria and USA) beginning 15 October and Moscow (Not available in Russia and USA)?starting 17 October. Watch Live Powered By TennisTV | TV Schedule
WEEK IN REVIEW
Top Tweets
?@DjokerNole (Novak Djokovic) Hope u'll accept my apology (once again) 4 giving u couple of heart attacks today. Seriously, I'm not doing it on purpose ;)
?@RSoderling (Robin Soderling) This morning me and @jennimostrom became parents to a beautiful little girl. We are all feeling great and are extremely happy.
?@TommyHaas13 (Tommy Haas) Seeing the Great Wall was a highlight, good times in China. Now a little layover in Dubai to one of my favorite city pic.twitter.com/jOAVzX6N
?@paul_annacone (Paul Annacone) can I change the shoe from 287 to 300 for total weeks at #1 ? - congrats RF tremendous effort pic.twitter.com/fCMtFmOl
?@colin_fleming (Colin Fleming) Really happy to get the win today in a battle of a match. Thru to our 1st Masters 1000 SF tomorrow! Thanks for the messages of support.
Most Popular Facebook Post on Facebook.com/ATPWorldTour
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Video Of The Week In season 4, episode 41, ATP World Tour Uncovered presented by Rio looks at the tense battle to qualify for the Barclays ATP World Tour Finals next month.
In Case You Missed It? Shanghai: World No. 2 Novak Djokovic saved five match points to dethrone two-time defending Shanghai Rolex Masters champion Andy Murray 5-7, 7-6(11), 6-3, lifting his fifth trophy of the season. Djokovic: ?It?s Going To Help Me In The Race For No. 1?
Djokovic vs. Murray Rivalry Intensifies Novak Djokovic and Andy Murray squared off for the?sixth time this?year in Shanghai. Djokovic?s levelled to 3-3 in their season meetings and 9-7 overall in their FedEx ATP Head2Head series. Catch up on their 2012 clashes in the chart below?
?Tournament
Round
Result
Australian Open
SF
Djokovic 6-3, 3-6, 6-7(4), 6-1, 7-5
Dubai
SF
Murray 6-2, 7-5
Miami
F
Djokovic 6-1, 7-6(4)
London 2012 Olympics
SF
Murray 7-5, 7-5
US Open
F
Murray 7-6(10), 7-5, 2-6, 3-6, 6-2
Shanghai
F
Djokovic 5-7, 7-6(11), 6-3
Tidbits ??Reigning Olympic and US Open champion Andy Murray has been named one of AskMen?s Top 49 Most Influential Men of 2012, joining a list topped by James Bond, Usain Bolt and Bill Clinton. More? ??Rainer Schuettler, the 2003 Australian Open finalist, has retired from tennis after a 17-year professional career. More? ??Max Mirnyi recorded his 600th doubles match win in the second round of the Shanghai Rolex Masters, partnering Daniel Nestor. More? ??The ATP has released a statement on the Australian Open prize money discussions. More? ??Dusseldorf will host an ATP World Tour 250 tennis tournament in the week before Roland Garros after leading promoter Ion Tiriac and Rainer Schuettler joined forces to acquire the tournament membership. More?
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Shanghai
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There is a clear parallel between music and perfumery, between olfactory and musical melodies, and we shall use this likeness in order to understand better the ?why? and the ?how? of olfactory education.
Just like music, perfumery is an art and even a major art, being entirely dedicated to one of our senses of perception, the sense of smell.Why is perfumery not taught at school just like music or drawing?Is perchance our sense of smell a minor sense of little importance?Do we perhaps love perfumes less than other civilizations?
School programs offer to all the basis of musical education, teaching the seven notes of our musical scale.
Olfactory education is no less important and to be able to name the scents of lavender and rose is no less important than to be able to name the blue and the red of the color spectrum.
The program that we deisigned is very simple and can be reassumed in one phrase: ?how to become a perfumer in 4 moves?.
1.) The Ability to Name Odors: In fact the basis of olfactory education is to be able to name the odors by their names, which is not as easy as it seems. Our primordial sense of smell situated in our ?reptilian brain? has little connection with the more evolved centers of language in our brain.
It is really surprising how often people, while smelling the absolute of coffee or the essence of lemon, smile over the bottle, recognizing only the happy memories associated with these familiar smells, without being able to give their names.
The basis and the first step of olfactory education consists in being able to name the scents that surround us. With a special diffuser, we send a sweet perfumed wind to the students and teach them to recognize the names of simple smells like lavender, pine, lemon ecc?
2.) Distinguishing the Components of a Perfume: The second step is to be able to distinguish the different components of a culinary creation or of the essences that compose simple blends such as orange cinnamon, rose lavender hay, ecc?For this course we use the perfumed wind organ, which allows us to combine 10 different essences in all possible combinations. 3.) Scent and Emotion Experiential Exercise: The third step of olfactory education is to develop the capacity to ?listen to the soul? while smelling a fragrance, and to become aware of the emotions it produces and of the memories it awakens. The exercise of describing them by words sums up the method, because by wording one conceptualizes, and by conceptualizing one intellectually appropriates the experiences. For this course we use the diffuser ?Cube? and familiar essences (lemon, mandarin, clove?) as well as totally new smells from other countries (vetyver, ylang ylang, patchouli?) In this course one learns the basis of the very special language of perfumers, which permits the description of fragrances just as landscapes or scenes are described. If you never heard the worlds ?round? or ?fresh? or ?deep? while smelling such characteristic fragrances, how could you ever describe a perfume or any odor.
The didactical path of these first three steps of olfactory education is directly inspired from the Japanese Kodo, ?the way of scent?, the Zen of olfaction.
4.) Team Composition of a Perfume: In the fourth step the students are given a simple and practical perfumer?s kit for children, and they are teamed by two. Everyone will make a perfume for his companion, with the same method that we use in our perfumery courses. At the end of this course every student will keep the bottle of his perfume.
A civilization produces musicians and musical culture only after its sons and daughters have received a musical education in their childhood.
Today, while the scents of nature essential to our psychological equilibrium are disappearing from our modern environment, chemical perfumes are omnipresent in our daily life, ice creams, soaps, cosmetics etc. This has created a confusion in the later generations because their olfactory models of reference are those that industrial marketing have provided for their consumption, the cheapest petrochemical mass products. Only an olfactory education can provide them with the knowledge necessary to apply criterions to the smells that surround them in order to judge their quality or to appreciate fully their beauty.
The World No. 9 looks to add valuable points at the Erste Bank Open in his bid to qualify for the Barclays ATP World Tour Finals. Tipsarevic is just outside the qualification cutline in ninth place, the position he finished in last year before competing as an alternate. He has a 53-22 season record, highlighted by his first clay-court title in Stuttgart (d. Monaco) and semi-final showings at the ATP World Tour Masters 1000 events in Madrid (l. to Federer) and Toronto (l. to Djokovic). The Serb also equalled his best major performance by reaching the US Open quarter-finals for a second straight year (l. to Ferrer).
Top Tweets
?
??The ATP has released a statement on the Australian Open prize money discussions. More? 